| Varyant (motor) | Kapı | Güç (b.g.) | Karoseri tipi | Azami hız | Start (yıl) | Son (yıl) |
|---|---|---|---|---|---|---|
| CLS 550 4.7 biturbo (408 Hp) | - | 408 | - | 250 km/saat | - | - |
| CLS 350 CDI BlueEFFICIENCY (261 Hp) | 4 | 261 | Kupe | 250 km/saat | 2011 | 2014 |
| CLS 350 BlueEFFICIENCY (302 Hp) | 4 | 302 | Kupe | 250 km/saat | 2011 | 2014 |
| CLS 250 CDI BlueEFFICIENCY (201 Hp) | 4 | 201 | Kupe | 242 km/saat | 2011 | 2014 |
